RsmG 甲基转移酶可修饰细菌 16S rRNA 的 G527 位点，其失活会赋予低水平链霉素抗性。而高水平链霉素抗性通常需要核糖体蛋白 uS12 或 16S rRNA 的特定改变。本研究探讨rsmG失活是否会改变一组随机生成的大肠杆菌 uS12 突变体的表型。

氨基糖苷类抗生素临床意义重大，但其耐药问题严峻。研究人员探究 16S rRNA 甲基转移酶（如 KamB、NpmA 等）与缺乏 RimM 和 YjeQ 的未成熟 30S 核糖体亚基的作用。结果发现这些酶可结合并修饰未成熟亚基，为干预耐药提供新方向。

Ribosomal RNA (rRNA) is a type of non-coding RNA that is a crucial component of ribosomes, the cellular machinery responsible for protein synthesis.Non-coding RNA refers to RNA molecules that are not ...

Please use one of the following formats to cite this article in your essay, paper or report: APA. Cheriyedath, Susha. (2023, April 07). Types of RNA: mRNA, rRNA and tRNA.

Since the beginning of the microbiome era decades ago, 16S rRNA gene-based amplicon sequencing has been widely adopted for microbial composition profiling. Many researchers might assume the 16S ...

Elimination of sequences with low quality scores can improve the accuracy of bioinformatics analyses. Compared with shotgun sequencing, this is more significant for 16S rRNA amplicon sequencing. For ...