Data on the relationship between ribosome biogenesis and p53 function indicate that the tumour suppressor can be activated by either nucleolar disruption or ribosomal protein defects. However, there ...

In eukaryotes, there are four rRNAs associated with ribosomes; these are the 18S, 5.8S, 28s, and 5S rRNAs. Production of the first three occurs within the nucleolus, whereas 5S rRNA production occurs ...

ERA, composed of an N-terminal GTPase domain followed by an RNA-binding KH domain, is essential for bacterial celi viability. It binds to 16S rRNA and the 30S ribosomal subunit. However, its ...

Translocation: The ribosome moves one codon down the mRNA. The tRNA in the A site moves to the P site, the tRNA in the P site ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, No. 27 (July 7, 2020), pp. 15609-15619 (11 pages) Ribosome biogenesis is a complex process, and dozens of ...

Two key sequencing techniques are no longer at odds, thanks to an international effort led by scientists at University of California (UC) San Diego. The researchers have developed a reference database ...

Removal of adapters, PCR primers, and low quality bases is a necessary step for quality control of sequences. And there are a variety of integrated tools have been developed for this purpose. ‘Q’ is ...

In a recent study posted to the bio Rxiv* pre-print server, a team of researchers investigated the existence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-host chimeric RNA and ...

A research group led by Prof. Guang Shouhong from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences, collaborating with Prof. Feng Xuezhu from the First ...