Methods and analysis We will recruit 478 paediatric patients with newly diagnosed IgAV across multiple centres. Participants will undergo prospective longitudinal assessment at disease onset and at 1, ...

Introduction Previous trauma and adverse life experiences have been hypothesised to be aetiological factors for functional neurological disorder (FND) leading to the hypothesis of a ‘trauma-subtype’ ...

Objectives To investigate the occurrence of depression and mental health disorders other than depression among Brazilian people with intellectual disabilities, analysing data from a national household ...

Introduction This project aims to comprehensively examine the incidence of suicidality, individual and population characteristics, and health pathways, for a cohort of Australian veterans using linked ...

Protocol: Clinical outcomes, cost-effectiveness and implementation of individualised physiotherapy using the Specific Treatment Of Problems of the Spine (STOPS) approach for chronic low back pain in ...

Introduction Mitochondrial dysfunction and disrupted cerebral energy metabolism have been increasingly linked to the pathophysiology of schizophrenia. Preclinical studies suggest that certain atypical ...

Introduction Intrapartum-related complications are a leading cause of adverse perinatal outcomes, including stillbirths, ...

Objectives Post-chronic pancreatitis (CP) diabetes mellitus (PPDM-C) is a distinct form of diabetes, in which complex pathogenesis hampers adequate glycaemic control. This study aimed to identify risk ...

Conclusion Considering the high price of the GLE/PIB compared with the available options in Iran, with the introduction of GLE/PIB into Iran’s drug list, insurance coverage and appropriate allocation ...

Objective Patients receiving haemodialysis are at very high risk of fragility fracture, yet there are no proven treatments for fracture prevention. We will advance a pilot study on the feasibility of ...

Objectives The inflammatory response from acute infection may trigger cardiovascular events. We aimed to estimate associations between microbiologically confirmed urinary tract infections (UTIs) and ...

9 Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK 10 Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK Introduction Pancreatic ductal adenocarcinoma (PDAC) ...