Whole-body CD8+ T-cell PET imaging can detect spatial and temporal localization of CD8+ T cells. To obtain insight into early CD8+ T-cell response to immunotherapy in patients with melanoma, a highly ...

Currently, PET scanner validation phantoms, methods, and acceptance criteria for clinical trials are not standardized. This situation generates substantial inefficiencies with many scanners being ...

We propose strongly unrealistic data augmentation to improve the robustness of convolutional neural networks (CNNs) for automatic classification of dopamine transporter SPECT against the variability ...

Owen Witte, MD, is recognized for multiple seminal contributions over the past 50 years impacting our understanding of human leukemias, immune disorders, and epithelial cancers, which have defined new ...

You don’t understand anything until you learn it more than one way. —Marvin Minsky (1927–2016) Living organisms maintain homeostasis through dynamic multiorgan systemic interactions (1). Considerable ...

Radiopharmaceutical therapy is growing rapidly. However, yet to be addressed is the implementation of methods to plan treatments for circulating tumor cells, disseminated tumor cells, and ...

Prostate-specific membrane antigen (PSMA)–targeting radiopharmaceuticals, such as the novel [177Lu]Lu-HTK03170, present a promising therapeutic option for metastatic castration-resistant prostate ...

252013 Introduction: The advent of total-body PET enabled the streamlined application of whole-body dynamic scans for highly quantitative Patlak parametric imaging of the tracers’ tissue net influx ...

Multiparametric MRI (mpMRI) and prostate-specific membrane antigen (PSMA) PET/CT are complementary imaging modalities used in the presurgical evaluation of patients with prostate cancer (PCa). The ...

177Lu-DOTATATE is an effective second-line treatment for metastatic or nonresectable neuroendocrine tumors. This treatment can result in hematologic severe adverse reactions (SARs). Preemptive ...

The introduction of total-body PET, or long–axial-field-of-view (LAFOV) PET, has led to high-quality imaging by improving sensitivity through its increased axial coverage and volume of detector ...

This study aimed to test and validate a dual-time-window (DTW) protocol for 6-(fluoro-18F)-3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine ([18F]MK6240) dynamic PET imaging in experimental ...