Currently, PET scanner validation phantoms, methods, and acceptance criteria for clinical trials are not standardized. This situation generates substantial inefficiencies with many scanners being ...

Whole-body CD8+ T-cell PET imaging can detect spatial and temporal localization of CD8+ T cells. To obtain insight into early CD8+ T-cell response to immunotherapy in patients with melanoma, a highly ...

dosimetry radiopharmaceutical therapy SPECT In parallel with the ongoing, dramatic growth in molecularly targeted radiopharmaceutical therapies (RPTs), there is intense interest in the development of ...

Intrapatient intermetastatic heterogeneity (IIH) has been demonstrated in metastatic castration-resistant prostate cancer (mCRPC) patients and is of the utmost importance for radiopharmaceutical ...

Johannes Tran-Gia, Francesco Cicone, Michel Koole, Francesco Giammarile, Jonathan Gear, Emmanuel Deshayes, Pablo Minguez Gabiña, Marta Cremonesi, Jonathan Wadsley ...

Prostate-specific membrane antigen (PSMA) is a promising target in prostate cancer. Recently, we started the first-in-human treatment with an α-radionuclide–labeled PSMA ligand. Although the case ...

lymphoscintigraphy sentinel lymph node breast cancer melanoma Lymphoscintigraphy refers to planar or tomographic imaging of a radioisotope in lymphatics, usually 99m Tc. Identification and ...

We propose strongly unrealistic data augmentation to improve the robustness of convolutional neural networks (CNNs) for automatic classification of dopamine transporter SPECT against the variability ...

Glypican-1 (GPC1) is overexpressed in several solid cancers and is associated with tumor progression, whereas its expression is low in normal tissues. This study aimed to evaluate the potential of an ...

The nuclear medicine field has seen a rapid expansion of academic and commercial interest in developing artificial intelligence (AI) algorithms. Users and developers can avoid some of the pitfalls of ...

EXECUTIVE SUMMARY The value of nuclear medicine imaging for diagnosing infections, was first recognized nearly 50 y ago (1). The 3-phase bone scan was for many years the radionuclide test of choice ...

Quantitative 18F-FDG PET is increasingly being recognized as an important tool for diagnosis, determination of prognosis, and response monitoring in oncology. However, PET quantification with, for ...