Cancer Research

American Association for Cancer Research

This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license. This work is licensed under a Creative Commons ...
Cancer Research

American Association for Cancer Research

Chimeric antigen receptor (CAR) T-cell therapy has demonstrated promising outcomes in treating leukemia, yet it confronts significant hurdles due to severe side effects like cytokine release syndrome ...
Cancer Research

Catalytic Inhibition of KAT6/KAT7 Enhances the Efficacy and Overcomes Primary and Acquired Resistance to Menin Inhibitors in MLL Leukemia

1Peter MacCallum Cancer Centre, Melbourne, Australia. 2Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Australia. 3Collaborative Centre for Genomic Medicine, Peter ...
Cancer Research

An Optimized Platform Overcomes Excessive Tumor Immune Rejection Induced by the CRISPR/Cas9 Lentiviral System

1Department of Thoracic Surgery, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, China. 2Department of Pathology and Frontier Innovation Center, School of Basic Medicine Sciences ...
Cancer Research

Detection of Human Brain Cancers using Genomic and Immune Cell Characterization of Cerebrospinal Fluid through CSF-BAM

1Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland. 2Ludwig Center for Cancer Genetics and Therapeutics, Johns Hopkins University School of Medicine, Baltimore, ...
Cancer Research

Gut Microbiota–Mediated Bile Acid Metabolism Regulates Colorectal Cancer Liver Metastasis by Altering Neutrophil Recruitment

1School of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China. 2Department of Oncology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, ...
Cancer Research

Phase Ib Basket Expansion Trial and Alternative-Schedule Dose-Escalation Study of ATR Inhibitor Elimusertib in Advanced Solid Tumors with DNA Damage Response Defects

1The University of Texas MD Anderson Cancer Center, Houston, Texas. *Corresponding Author: Timothy Yap, Department for Investigational Cancer Therapeutics (Phase I Program), Division of Cancer ...
Cancer Research

From Discovery to Diagnosis: A Perspective for Circulating Tumor Cells in Personalized Oncology

1Laboratory of Rare Human Circulating Cells (LCCRH) and Liquid Biopsy, University Medical Centre of Montpellier, Montpellier, France. 2CREEC (CREES), Unité Mixte de Recherches, IRD 224–CNRS ...
Cancer Research

Malonyl-CoA Promotes Prostate Cancer Progression and Castration Resistance by Enhancing Lipogenesis and Ran Activation

1Department of Urology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China. 2Department of Urology, Henan Institute of Urology and Zhengzhou Key Laboratory for Molecular Biology of ...