Background Depending on the colorectal cancer (CRC) screening programme, a colonoscopy should be performed within 1–3 months ...

Background Chronic hepatitis B virus (HBV) infection disproportionately affects people living with HIV, who are often excluded from functional cure studies. Objective This study investigates CD8+ T ...

Chronic HBV infection remains a major global health burden, with current antiviral therapies effectively suppressing viral ...

We read with great interest the article of Ratziu and colleagues, who evaluated the potential of thrombospondin-2 (TSP2), insulin-like growth factor binding protein 7, CD163 and growth differentiation ...

Background The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) is rapidly increasing with high ...

Background Diffuse gastric cancer (DGC) is the most common manifestation in germline CTNNA1 variant carriers, with one study estimating a 49–57% lifetime risk by age 80. Knowledge on CTNNA1-associated ...

Recent studies have identified mucosal healing on endoscopy as a key prognostic parameter in the management of inflammatory bowel diseases (IBD), thus highlighting the role of endoscopy for monitoring ...

Background Endometriosis is a debilitating gynaecological disorder with an elusive pathogenesis. While gut microbiota dysbiosis has been implicated, the causal role of gut-peritoneum microbial ...

2 Department of Internal Medicine, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan 3 Department of Internal Medicine, GI Unit, Massachusetts General Hospital, Boston, Massachusetts, USA 4 ...

9 Wrightington Wigan and Leigh NHS Foundation Trust, Wigan, UK Background Acute upper gastrointestinal bleeding (AUGIB) is a common medical emergency with evolving demographics and management ...

4 Department of Gastroenterology, Hepatology and General Medicine, Royal Adelaide Hospital, Adelaide, South Australia, Australia Correspondence to Dr Hashem B El-Serag, Section of Gastroenterology and ...

Background and aims: Ulcerative colitis disease activity indices offer good statistical power but small changes in these indices may not be clinically important. There are no validated definitions of ...