Ischemic stroke in younger adults is far less common than that among older adults, yet the underlying pathogeneses and risk factors are more diverse. Approximately 10% to 15% of all strokes occur in ...

Background—MicroRNAs (miRs) are small noncoding RNAs that posttranscriptionally control gene expression. Small-animal studies suggest that miRs might offer novel therapeutic targets in cardiovascular ...

Cardio-oncology has organically developed as a new discipline within cardiovascular medicine as a result of the cardiac and vascular adverse sequelae of the major advances in cancer treatment.

Smooth muscle cell migration occurs during vascular development, in response to vascular injury, and during atherogenesis. Many proximal signals and signal transduction pathways activated during ...

STRUCTURE: This guideline provides an evidenced-based and patient-centered approach to management of patients with chronic coronary disease, considering social determinants of health and incorporating ...

Background— The ability to derive human induced pluripotent stem (hiPS) cell lines by reprogramming of adult fibroblasts with a set of transcription factors offers unique opportunities for basic and ...

These guidelines contain recommendations for pediatric basic and advanced life support, excluding the newborn period, and are based on the best available resuscitation science. The Chain of Survival ...

Measurement of blood pressure (BP) in the upright posture is recommended by all hypertension guidelines to detect orthostatic hypotension especially in elderly patients. 1 However, a number of studies ...

We analyzed data from 113 918 newly diagnosed patients with dyslipidemia (2009–2012) without prior CVD, sourced from the Korea National Health Insurance Service. Ambient particulate matter (PM) 2.5 ...

In this study, FFR and μQFR were assessed in 497 intermediate stenoses (30%–70% by visual estimation) from 460 patients (34.3% female). Physiological significance was defined as FFR ≤0.80 or μQFR ...

In contrast to therapeutic trial results, observational data from the National Health and Nutrition Survey (NHANES) have predicted a relatively lower prevalence of resistant hypertension. Analyzing ...

Rationale:Recent evidence indicates that a few human microRNAs (miRNAs), in particular hsa-miR-199a-3p and hsa-miR-590-3p, stimulate proliferation of cardiomyocytes and, once expressed in the mouse ...