Background Traumatic brain injury (TBI) is common in military campaigns and is a risk factor for dementia. ArmeD SerVices TrAuma and RehabilitatioN OutComE-TBI (ADVANCE-TBI) aims to ascertain ...
Background Cerebral amyloid angiopathy (CAA) is a common cause of intracerebral haemorrhage (ICH) with a high recurrence risk. Left atrial appendage occlusion (LAAO) is a method for ischaemic stroke ...
Introduction Frequent focal seizures are a hallmark of encephalitis with antibodies to leucine-rich glioma-inactivated 1 (LGI1-Ab-E) in humans. Recently, LGI1-Ab-E has emerged as an important cause of ...
Background The Problem Behaviors Assessment – Short Form (PBA-s) is a widely used measure of behavioral symptoms in HD research given its comprehensiveness and development for use with people with ...
Introduction Gerstmann-Sträussler-Scheinker (GSS) syndrome, caused by the PRNP P102L mutation is cha- racterized by slowly ascending distal lower limb sensory loss, cerebellar ataxia, pyramidal signs, ...
Functional Neurological disorder (FND) is a common, disabling condition which is often seen in Neurology Clinics. There are significant challenges associated with making the diagnosis accurately and ...
Background Functional motor disorders (FMD) cause long-term disability and economic burden. There is a need for multidisciplinary interventions to manage both motor and non-motor symptoms. We aim to ...
Background Disease-modifying therapies (DMTs) for Alzheimer’s disease (AD) have early evidence of efficacy. Widespread delivery of DMTs will require major service reconfiguration. Treatment pathways ...
Immune checkpoint inhibitors (ICI) have had a dramatic effect on cancer outcomes with their use increasing as indications expand. Despite impressive efficacy across a range of tumour types, their role ...
Background Reports of primary angiitis of the central nervous system (PACNS) are mainly restricted to clinically suspected cases, but biopsy-proven ones are rare. Here, we present results from a large ...
Background Stereotactic thrombolysis reduces intracerebral haemorrhage (ICH) volume in patients with spontaneous ICH. Whether intrahaematomal alteplase administration is associated with a change in ...
3 South West London and Saint George’s Mental Health NHS Trust, London, UK 4 King’s College Hospital NHS Trust, London, UK Deep brain stimulation (DBS) is a surgical treatment for medication-resistant ...
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