在脊椎动物胚胎发生过程中，轴向肌腱从轴旁中胚层发育而来，并经过特定的发育阶段分化至肌腱节阶段。虽然信号通路在分化早期阶段的主要作用已得到充分证实，但从肌腱节阶段开始，肌腱节分化过程中通路的细微差别尚待探索。本文，我们展示了使用基于 ...

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Research Objective We propose to discover a novel, genetically modified hematopoietic stem cell based treatment for Danon disease, a rare lysosomal storage disease that affects the heart. Impact As ...

Chronic kidney disease affects 10% of Americans. Over 700,000 receive dialysis. The long-term prognosis for the dialysis patient is poor. A renal transplant can provide a cure but there are too few ...

CIRM funds stem cell research to institutions throughout California. On the map below, click on any marker to learn more about our funding to that institution. You can explore the awards they’ve ...

South San Francisco, Calif., January 30, 2026 – The California Institute for Regenerative Medicine (CIRM) has approved a new funding program to accelerate therapies for rare diseases, which sets aside ...

When most people think about about stem cells treating disease they think of a stem cell transplant. In a stem cell transplant, stem cells are first specialized into the necessary adult cell type.

Through its strategic funding of clinical trials, CIRM helps advance innovative stem cell and gene therapy discoveries toward future treatments for patients. CIRM funds clinical trials across a broad ...

The mission of the California Institute for Regenerative Medicine (CIRM) is to accelerate world class science to deliver transformative regenerative medicine treatments in an equitable manner to a ...

CIRM board supports a rare disease funding plan, administrative changes January 30, 2026 Written by Holly Alyssa MacCormick South San Francisco, CA, January 30, 2026 – As many as 1 in 10 people in the ...

The proposed program will provide high school students with an excellent opportunity to be exposed to stem cell research. It will inform and increase the awareness of high school students in stem cell ...

The California Institute for Regenerative Medicine (CIRM) was established in 2004 when 59 percent of California voters passed Proposition 71, also known as the California Stem Cell Research and Cures ...