Our findings provide insights into previously uncharacterized dynamics at the cancer cell–cytotoxic lymphocyte interface, uncovering a critical mechanism by which actin cytoskeleton remodeling at the ...

The coaggregation of amyloid-β (Aβ) and α-synuclein (αSyn) has been implicated in Alzheimer’s and Parkinson’s diseases, yet the molecular mechanisms behind these processes remain elusive. By ...

Bacteria encode a variety of reverse transcriptases (RTs) that evolved from mobile group II intron RTs to perform different cellular functions. A previous study found that one such domesticated group ...

In an increasingly fractured world, it is vital to understand when and why people cooperate with and trust others. Traditional social science techniques infer motivations from observed behaviors. We ...

Plants respond to external stresses by redistributing resources from growth- to defense-related processes, often resulting in decreased yields. This results in growth–defense trade-offs, where ...

The regulated secretion of insulin and glucagon is exceptionally important for the maintenance of normal blood glucose, including the prevention of hypoglycemia. Local release of the inhibitory ...

Riverine heat wave events—periods of abnormally high riverine water temperatures (WT)—can substantially impair aquatic ecosystems, water quality, and food and energy production. However, comprehensive ...

This study demonstrates the feasibility and accuracy of a wearable microfluidic sweat patch (CF Patch) for remote monitoring of sweat chloride concentrations in people with cystic fibrosis (PwCF). By ...

Understanding why certain diseases tend to co-occur is key for improving patient outcomes. This study introduces an approach to map disease co-occurrences using large-scale RNA sequencing data, ...

Sustained electrophysiological signals play a critical role in powering the autonomous function of excitable tissues, such as those found in the heart. Traditional approaches to mimicking this ...

Abiotic organic synthesis in geological processes is closely linked to the Earth’s carbon cycle and the origin of early life. Our research revealed that the infiltration of ferrous chloride–rich ...

Cities can be viewed as living organisms and their metabolism as the set of processes controlling their evolving structure and function. Urban population, transport networks, and all anthropogenic ...