Before cells can divide by mitosis, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Scientists have until now ...

MIT researchers discovered that the genome’s 3D structure doesn’t vanish during cell division as previously thought. Instead, tiny loops called microcompartments remain (and even strengthen) while ...

Organoids—self-organizing, self-reproducing structures that serve as 3D in vitro models—date back to 2009. Back then, researchers at the Hubrecht Institute led by Hans Clevers, PhD, introduced a ...

In a major leap forward for genetic and biomedical research, scientists have developed a powerful new artificial intelligence tool that can predict the 3D shape of chromosomes inside individual cells ...

Gene editing is one of the latest breakthroughs in biology. The widely known CRISPR-Cas gene editing system provided prokaryotes (organisms that lack cell nuclei) an immunity against foreign DNA.

Two new landmark studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published March 3 as two papers in ...

At the University of Tokyo, Prof. Osamu Nureki's group works on identifying the structure and function of the proteins involved in genome editing. In a recent study by the team, they discovered the 3D ...

In a first, scientists have mapped the three-dimensional structure of DNA belonging to an ancient animal: a 52,000-year-old mammoth found sporting a mulletlike hairdo. This advance, published in Cell, ...

This 3D reconstruction of a melanoma cell provides scientists with valuable insights into the structure, function, and spread of this deadly cancer. This 3D reconstruction of a melanoma cell provides ...