Understanding human gene function in living organisms has long been hampered by fundamental differences between species. Although mice share most protein-coding genes with humans, their regulatory ...

There are many successful examples of treatments that were used in animal health care before being used in humans. Indeed, not soon after the approval of Zoetis’ interleukin 31 (IL-31)-targeting ...

A human-specific NOVA1 variant changed mouse vocalizations, potentially providing insights into the evolution of language. Darnell said the switch to the new NOVA1 variant likely occurred between ...

A single-chain Fv antibody fragment specific for the tumor-associated Ep-CAM molecule was isolated from a semisynthetic phage display library and converted into an intact, fully human IgG1 monoclonal ...