It is well known that apoptosis is an actively mediated cell suicide process. In contrast, necrosis, a morphologically distinct form of cell death, has traditionally been regarded as passive and ...

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis in various tumor cells in vitro, but its physiological role in tumor surveillance remains unknown. Here, we report ...

Tumour necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptors (TRAILR1 and TRAILR2) are promising targets for cancer therapy: both recombinant TRAIL and monoclonal antibodies ...

Abstract—The programmed form of cell death (apoptosis) is essential for normal development of multicellular organisms. In the past few years, compelling evidence accumulated that dysregulation of ...

Proteins involved in neuroinflammation found in the cerebrospinal fluid could help researchers better diagnose and treat ...

Death and life have been considered for millennia as complete opposites, a binary switch with permanent reversal. But creative new research suggests a possible third state of life whereby cells ...

Most shockingly, diquat was dubbed "the worst offender" of the four weed killers. "It is 200 times more chronically toxic ...

Parasitic tapeworm larvae release glutamate and other excitatory molecules that can directly excite brain neurons.

Spirulina is a nutrient-dense cyanobacterium rich in proteins, phycobiliproteins, carotenoids, and polyphenols that deliver ...

Cortical laminar necrosis (CLN) is a selective cortical necrosis primarily involving layer 3 of the cortex. Its causes, clinical features, and outcomes in pediatric patients remain unclear due to ...

Di-(2-ethylhexyl) phthalate (DEHP), a ubiquitous environmental pollutant, significantly impairs the male reproductive function. Astaxanthin (ASX), a natural carotenoid with potent antioxidant ...

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