Caspase-8 mediates apoptosis induced by 'death receptors' on the cell's surface. At the same time, it is able to prevent receptor interacting protein kinase (RIPK)-dependent necrosis. Without ...

We conclude that UCB induces early necrosis at high and moderate concentrations and predominantly delayed apoptosis at low and moderate concentrations in cultured human NT2-N neurons.

Unlike necrosis, which is a pathologic process, apoptosis is part of normal development (physiologic apoptosis); however, it also occurs in a variety of diseases (aberrant apoptosis).

Listen in as our scientific expert, Miriam Ferrer, Ph.D, reviews tips and techniques to help you easily distinguish what type of cell death is present in your experiment, including morphological ...

Necrosis and Apoptosis are crucial for multicellular homeostasis, but it also plays an ill-fated role in human disorders.

While apoptosis neatly removes select cells, necrosis destroys without strategy. Accordingly, the process of necrosis is much messier.

ImmunoChemistry Technologies’ Necrosis vs. Apoptosis Assay Kit can help developers monitor overall cell-line health as well as cytotoxic responses.

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a type 2 membrane protein of the TNF superfamily.

Move Over Apoptosis: Another Form of Cell Death May Occur in the Gut Though scientists don’t yet know much about it, a newly described process called erebosis might have profound implications for how ...

Many cancers have developed sophisticated mechanisms to do this by hijacking components of the apoptosis, necrosis, and autophagy signaling pathways.