Scientists are urgently seeking fluid biomarkers for frontotemporal dementia, the most common dementing illness among 40- and ...

Disparate pathogenic mechanisms complicate precision-medicine efforts to treat diffuse large B-cell lymphoma (DLBCL), the most common lymphoma diagnosis. Though potentially curable with frontline ...

Apoptosis is a mechanism of programmed cell death and is essential for development and homeostasis. Cell stress stimulates pro-apoptotic signalling pathways that activate caspase proteases and ...

“We’re excited about the potential of this new strategy,” said Dr. Xiaowei “George” Xu, a Penn Pathology and Laboratory Medicine professor. “Our preclinical results are promising, and we’re eager to ...

Mitochondria are critical for cellular homeostasis, regulating bioenergetics, redox balance, Ca2+ signaling, and cell death. Mitochondrial Ca2+ (Ca2+mito) plays a dual role in physiological processes ...

When activated, DR5 can trigger the death of these cells by a self-destruct process called apoptosis ... professor of Pathology and Laboratory Medicine, and member of the Tara Miller Melanoma ...

When activated, DR5 can trigger the death of these cells by a self-destruct process called apoptosis ... a professor of Pathology and Laboratory Medicine, and member of the Tara Miller Melanoma ...

Department of Respiratory and Critical Care Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, Institute of Respiratory Health, Frontiers Science Center for Disease-related ...