which promotes apoptotic cell death. In the RB pathway, stress signals such as oncogenes induce INK4A, the other product of the CDKN2A locus. INK4A inhibits CDKs that phosphorylate, and therefore ...

This opioid pathway in the brain was specifically activated when the mice ate additional sugar, but not when they ate normal or fatty food. When the researchers blocked this pathway, the mice ...