(Nanjing, China); Annexin V-FITC/PI Cell Apoptosis Kit (No ... indicating that the compound specifically targets the activation state of these signaling molecules rather than their overall expression.

Introduction: BAP1 is a deubiquitinase (DUB) of the Ubiquitin C-terminal Hydrolase (UCH) family that regulates gene expression and other cellular processes, through its direct catalytic activity on ...

Using an unbiased approach, this important study discovered a role of Ezh2 in the differentiation of granule neuron precursors, the cell of origin for Shh group of medulloblastoma. Furthermore, the ...

Intravascular large B-cell lymphoma (IVLBCL) is a rare type of non-Hodgkin’s lymphoma. Its symptoms can vary, making it difficult to diagnose. The outlook for people with IVLBCL is typically poor.

today announced the activation of its first clinical trial site at The University of Texas MD Anderson Cancer Center for its Phase 1 study evaluating BTM-3566 in relapsed/refractory mature B-cell ...

Learn more about eLife assessments Sleep disturbances are associated with poor long-term memory (LTM) formation, yet the underlying cell types and neural circuits involved have not been fully decoded.

Cancer is a major global cause of death, resulting in millions of new cases being diagnosed every year. Chemotherapy, radiotherapy, and surgery have led to considerable advancements in patient ...

T cell engagers are antibodies that are engineered to recognize and kill harmful cells, be it tumor cells in the case of cancer or autoreactive cells in the case of autoimmune diseases. They achieve ...

Wildfire smoke exposure acutely increased IL-13 expression in NK cells and was negatively associated with COVID-19 vaccine immunity.

Bantam Pharmaceutical, a drug discovery and development company targeting selective modulation of mitochondrial dynamics in cancer, today announced it is proceeding with a Phase 1 clinical trial ...