Learn how analytical methodologies can be used to identify RSV pre- and post-fusion proteins for vaccine development.

By targeting surface markers on cancer cells, engineered synthetic receptors expressed on immune cells can be directed to ...

LATS1/2-inactivation and consequent nuclear YAP/TAZ hyperactivation in the mammary epithelium drives the development of a pro ...

Aneuploidy is frequent in cancer, but in vitro it triggers multiple cellular stresses and often delays proliferation. Through ...

The protein–protein interaction between ACE2 and the higher affinity mAb ... MA, USA). In the serum preadsorption assay, ELISA strip wells (Corning) were coated with BSA (10 μg/mL, 100 μL), S1-RBD (10 ...

This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

Once confined to sportsmen and women, high-protein diets are now commonplace – with Paleo, Atkins, Zone and Dukan advocating that people eat large quantities of fish, meat, eggs, nuts and cheese ...

Protein design (or protein engineering) is a technique by which proteins with enhanced or novel functional properties are created. Proteins can be engineered by rational design, which typically ...

Due to proteostasis stress induced by aging or disease, misfolded proteins can form toxic intermediate species of aggregates and eventually mature into less toxic inclusion bodies (IBs). Here, using a ...