Here, we explore the interaction between IgAV and inflammatory factors using bidirectional Mendelian randomization (MR). Methods: We conducted a bidirectional summary-level MR analysis to delineate ...

Feb. 11, 2025 — Scientists have discovered that some tiny segments of RNA thought to be junk instead have a functional role in suppressing production of certain messenger RNAs and appear to help ...

to uncover the genetic and molecular basis of a rare and complex Mendelian condition. In collaboration with the University of Washington and the Undiagnosed Diseases Network (UDN), the study ...

Methods In the Copenhagen General Population Study, we did an observational analysis in 28 845 individuals (2278 asthma cases) with plasma adiponectin measurements, and a genetic one-sample Mendelian ...

The aim of this study was to investigate the relationship between gout status and kidney stones and to further explore the causal relationship by Mendelian randomization (MR ... are randomly assigned ...

MENLO PARK, Calif., Feb. 13, 2025 (GLOBE NEWSWIRE) -- PacBio (NASDAQ: PACB) today announced financial results for the quarter and fiscal year ended December 31, 2024. Revenue of $39.2 million, a 33% ...

To install the BASIC interpreter to your own SMART Response XE, [Dan] goes over the process of flashing it to the hardware using an AVR ISP MkII and a few pogo pins soldered to a bit of perboard.

Objective To scope the potential for (semi)-automated triangulation of Mendelian randomisation (MR) and randomised controlled trials (RCTs) evidence since the two methods have distinct assumptions ...

This relationship has policy relevance, but is challenging to ascertain in observational data due to substantial risk of confounding. Mendelian randomisation (MR) exploits natural genetic variation as ...

PND was performed in subsequent pregnancies of mothers of four de novo cases. A fifth mother opted for preimplantation genetic diagnosis because of a coexisting Mendelian genetic disorder. The mtDNA ...