Objective To characterise gut microbiome in patients with hepatocellular carcinoma (HCC) and evaluate the potential of microbiome as non-invasive biomarkers for HCC. Design We collected 486 faecal ...

Drug-induced liver injury (DILI) is a significant concern in clinical practice, arising from medications, herbs, and dietary supplements.

Hepatocellular DILI is linked to inflammation ... Additionally, the use of biomarkers to monitor treatment efficacy could help refine the clinical application of UDCA. UDCA is a multifaceted ...

When tested in our DILI assay, cell health and functional biomarkers flagged troglitazone’s hepatotoxic risks, whereas pioglitazone showed no hepatotoxic effect. Tools like PhysioMimix allows ...

The technologies are now available to begin large-scale efforts to identify and validate new biomarkers of DILI. Registries and tissue banks created by DILIN and the Severe Adverse Events ...

Introduction: Acetaminophen (APAP) is widely used as an analgesic and antipyretic. However overdose APAP can lead to acute liver injury (ALI), representing a significant challenge for public health ...

Aero Dili (8G, Dili) has commenced scheduled passenger services between Dili and Xiamen, its first route to China. The first of the 2x monthly roundtrips operated on February 14, 2025. According to a ...