Drug-induced liver injury (DILI) is a significant concern in clinical practice, arising from medications, herbs, and dietary supplements.

Hepatocellular DILI is linked to inflammation ... Additionally, the use of biomarkers to monitor treatment efficacy could help refine the clinical application of UDCA. UDCA is a multifaceted ...

When tested in our DILI assay, cell health and functional biomarkers flagged troglitazone’s hepatotoxic risks, whereas pioglitazone showed no hepatotoxic effect. Tools like PhysioMimix allows ...

The technologies are now available to begin large-scale efforts to identify and validate new biomarkers of DILI. Registries and tissue banks created by DILIN and the Severe Adverse Events ...

Introduction: Acetaminophen (APAP) is widely used as an analgesic and antipyretic. However overdose APAP can lead to acute liver injury (ALI), representing a significant challenge for public health ...

Aero Dili (8G, Dili) has commenced scheduled passenger services between Dili and Xiamen, its first route to China. The first of the 2x monthly roundtrips operated on February 14, 2025. According to a ...

A biomarker is a biological characteristic that is objectively measured and evaluated as an indicator of normal biological or pathological processes, or a response to a therapeutic intervention ...

Northwestern Medicine investigators have discovered how proteins expressed in umbilical cord blood at birth evolve during gestational development and could serve as biomarkers to inform new ...

Researchers at the University of Pittsburgh have devised a biomarker test that can spot small amounts of clumping tau protein in the brain and cerebrospinal fluid, which lead to Alzheimer's disease.

Researchers define the structural regions of soluble tau assemblies. STA cores could be biomarkers for pretangle tau. They are found in cerebrospinal fluid. Others were impressed by the work. “This ...

Lautenberg Environmental Health Sciences Laboratory, Department of Environmental Medicine and Climate Science, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States ...