The biosynthesis of fumitremorgin-type alkaloids begins by condensation of the two amino acids L-tryptophan and L-proline to brevianamide F, catalyzed by the non-ribosomal peptide synthetase FtmPS ...

THE origin of the tropane (and other) alkaloids in the plants that produce them has not been the object if much interest in the past. This seems to have been due to the sterility of the ...

Plants produce a wide diversity of compounds. Broadly, these are separated into primary metabolites, which are necessary for ...

Tropane alkaloids are a particular class of plant-derived compounds that have been exploited by mankind since the domestication of medicinal plants. The distribution of these alkaloids is ...

Researchers identify last remaining steps in the biosynthesis of tropane alkaloids from Coca. ScienceDaily. Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2022 / 11 / 221121213656.htm.

By using single-cell analyses, the scientists were able to discover new genes important for biosynthesis and show that the intermediates of the metabolic pathway accumulate in specific cell types. The ...

Tropane alkaloids are a particular class of plant derived compounds that have been exploited by mankind since the domestication of medicinal plants. The distribution of these alkaloids is scattered ...

The team published its study, “Biosynthesis of medicinal tropane alkaloids in yeast,” in Nature. “Tropane alkaloids from nightshade plants are neurotransmitter inhibitors that are used for ...

The biosynthesis of the great variety of natural plant products has not yet been elucidated for many medically interesting substances. In a new study, an international team of researchers was able ...

Tropane alkaloids (TAs) are heterocyclic nitrogenous metabolites found across seven orders of angiosperms, including Malpighiales (Erythroxylaceae) and Solanales (Solanaceae). Despite the well ...

Alkaloids constitute a very large group of natural nitrogen-containing compounds with diverse effects on the human organism. A large variety of plant-produced alkaloids have strong pharmacological ...

In a recent study published in Nature , researchers successfully produced tropane alkaloids – medicines that have a wide variety of applications, including treating conditions as diverse as ...