In the gut, 5-HTT is located in epithelial cells, and its function is to inactivate locally ... although only three are expressed in bone 4. These findings suggest that Lrp5-related bone diseases ...

provides support and protection for vital organs and makes blood cells. Skeletal muscles move the bones in the body. The skeletal system is made from bones and joints. The femur bone in the thigh ...

Researchers have identified Type R capillaries’ importance in bone remodelling in mature and ageing bones. This shows that ...

Many of these genes regulate the bone matrix, but a large number of the genes have never been studied in bone before ...

Bone-marrow-derived multipotent progenitor ... which is enhanced by interferon-γ released by activated T cells. MSCs also impair B-cell functions, such as antibody production.

Hidden within our bones, marrow sustains life by producing billions of blood cells daily, from oxygen-carrying red cells to immune-boosting white cells.

Until now, it has not been understood how these cells function in the low-oxygen microenvironment of bone. Researchers at the Max Planck Institute for Molecular Biomedicine have achieved a ...

Osteoporosis is typically treated with orally administered drugs, which may take up to a year to have a noticeable effect. A ...

and enhancing bone-building cell (osteoblast) function, and which at the same time can deliver localized drug treatments to suppress tumor activity and support bone regeneration." Professor Dirk ...

Bone marrow plays a crucial role in maintaining hematopoietic stem cells and bone homeostasis. However, research has been hindered by a lack of effective markers and monoclonal antibodies to ...