On Dec 19, 2025, the US Food and Drug Administration (FDA) announced a major milestone by qualifying total hip bone mineral density (BMD), assessed by dual-energy X-ray absorptiometry, as a surrogate ...

In the elderly, a multitude of factors contribute to diminished bone regeneration capabilities, including a reduction in the self-renewal and differentiation abilities of mesenchymal stem cells, an ...

Skeletal stem cells (SSCs) are essential for bone development, homeostasis, and repair. Recent studies have identified distinct SSC populations in long bones, craniofacial bones, and spine. Techniques ...

Full view of how bones and joints form in the first trimester uncovers cells and pathways that could help diagnose and treat skeletal conditions in the future. The first 'blueprint' of human skeletal ...

SSCs are heterogeneous in nature, contributing to the development of long bones, craniofacial structures, and the spine. These SSCs have important functions in a variety of physiological and ...

In a study published in Cell Research, researchers have identified a fibrous-layer resident subpopulation of P-SSCs labeled ...

A recent study by the University of Eastern Finland is the first to report that the fatty acid composition of blood and the enzyme activity associated with it predict the development of bone mineral ...

A study conducted by researchers at Baylor College of Medicine and collaborating institutions reveals the molecular events leading to osteogenesis imperfecta type V, a form of brittle bone disease ...

Bone anchors are crucial in orthopedic surgeries, aiding in fracture fixation, soft tissue reattachment, deformity correction, osteochondral defect repair, and fusion. Existing bone anchors face ...

Skeletal conditions such as developmental dysplasia of the hip (DDH), osteoporosis, and osteoarthritis affect millions worldwide, often causing chronic pain and disability. These disorders stem from ...

Intermuscular bones (IBs) are slender ossified segments embedded within the myosepta of lower teleost fishes. Formed through a process of intramembranous ossification, these structures play a dual ...