Bone tissue engineering and regeneration stands at the forefront of regenerative medicine, offering innovative solutions for skeletal repair and reconstruction. This multidisciplinary field integrates ...

Bone tissue is a complex structure, consisting of mineralized collagen fibers and a variety of non-collagenous proteins, including proteoglycans such as biglycan and decorin. These proteoglycans ...

A recent study has uncovered the essential roles of two proteoglycans, biglycan and decorin, in maintaining bone mass, water retention, and bulk/in situ mechanical competence. Through the use of ...

Bone fractures usually heal efficiently, but in some patients this process fails, causing nonunion. A recent study identifies ...

Osteocytes, the most abundant cells in bone tissue, have long been underestimated in their functional capacity. Traditionally viewed as passive entities, recent research has illuminated their pivotal ...

To gain insight into age-related changes in bone healing, Reeves and colleagues studied how the periosteum and suture mesenchyme change with age in a mouse model. First, they analyzed the changes that ...

A new paper in JAMA Network Open determines whether type 2 diabetes mellitus (T2DM) increases the risk of fractures in older women. Diabetes affects over 500 million individuals worldwide, and its ...

We all live by checklists.Career goals? Ticked. Family milestones? Ticked. Travel plans, fitness streaks, weekend catchups - ...