Cell proliferation was determined by a BrdU assay (Roche Applied Science, Indianapolis, IN, USA) measuring the incorporation of the pyrimidine analogue, 5-bromo-2′-deoxyuridine (BrdU) during DNA ...

Assays to assess the proliferative activity of cells grown in culture or harvested from tissue samples are a core tool for monitoring the health and growth rate of a cell population.

Proliferative capacity assay: BrdU incorporation assay. We found that approximately 6.1% ±2.4% of the cells were positive for BrdU incorporation at day 7, ...

Each of these protocols is described in great detail, making this paper an excellent resource for scientists who want to attempt an assay to assess DNA damage. * Abstract from Nature Protocols ...

Each assay has specific advantages and disadvantages. For example, BrdU assays, a common DNA synthesis cell proliferation analysis method, has the advantage of single-cell resolution, but can ...

The Medicare decision is supported by strong evidence validating the assay's accuracy, backed by over 100 clinical studies. At the 2025 ASCO Annual Meeting, Natera presented a pan-cancer study ...

A noninvasive clinicopathologic and gene expression profiling (CP-GEP)–based tool, the Merlin assay, shows promise for identifying recurrence risks in patients with early-stage melanoma who do ...