Scientists Capture First-Ever Images of Cancer’s Covert DNA Repair Strategy
A new structural blueprint paves the way for improved targeting of cancer cells, particularly those with BRCA1 and BRCA2 ...
Medical Xpress on MSN13 天
How a crucial DNA repair protein works—and what it means for cancer treatment
DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers ...
Nature11 天
Double-strand DNA breaks articles from across Nature Portfolio
A double-strand DNA break (DSB ... microscopy to show how the helicase domain of DNA polymerase θ aligns broken DNA strands by matching short sequences, a process linked to cancer.
EurekAlert!13 天
How a crucial DNA repair protein works—and what it means for cancer treatment (IMAGE)
The Pol-theta enzyme (blue) joins two parts of a broken DNA strand (yellow). This process is mutagenic and can give rise to cancer.
EurekAlert!14 天
How a crucial DNA repair protein works—and what it means for cancer treatment
The Pol-theta enzyme (blue) joins two parts of a broken DNA strand (yellow). This process is mutagenic and can give rise to cancer. LA JOLLA, CA—DNA repair proteins act like the body’s editors ...
Why aged oocytes struggle to repair DNA damage
They are formed in a woman's body before birth and have to be on standby for decades to possibly be fertilized one day. But ...
Technology Networks13 天
Mechanism of Key DNA Repair Protein Advances Cancer Treatment
Scientists at Scripps Research have now captured the first detailed images of the DNA repair protein, Pol-theta, in action, ...
Supercomputer draws molecular blueprint for repairing damaged DNA
Sunburns and aging skin are obvious effects of exposure to harmful UV rays, tobacco smoke and other carcinogens. But the effects aren't just skin deep. Inside the body, DNA is literally being torn ...