The prize honored discoveries that defined peripheral immune tolerance through regulatory T cells (Tregs) and the FOXP3 gene, ...

On cycle 1 day 8, CS2009 induced notable, dose-dependent upregulation of Ki67 (proliferation due to PD-1 and CTLA-4 blockade) and ICOS (activation due to CTLA-4 blockade) expression on both CD4+ and ...

初始 T 细胞（Naive T cell，也叫做幼稚 T 细胞）是一类未接触过抗原的 T 细胞，处于静息（未活化）状态，它们尚未经历抗原特异性激活，但具有识别抗原的潜能，识别特异性抗原后，它们可分化为效应 T 细胞或记忆 T 细胞。

SCG Cell Therapy Pte Ltd (SCG), a clinical-stage biotechnology company developing next-generation immunotherapies for infectious diseases and their associated cancers, announced the presentation of ...

The 2025 Nobel Prize in Physiology or Medicine has been awarded to three scientists who discovered how our bodies keep this ...

Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi were awarded the prize "for their discoveries concerning peripheral immune tolerance" ...

Scientists have found a way to transform hard-to-treat tumors into targets for the immune system. Using two protein stimulators, they activated strong T-cell and B-cell responses and built immune ...

Talha Burki speaks with Fred Ramsdell, Mary Brunkow, and Shimon Sakaguchi about their Nobel-winning discoveries in peripheral immune tolerance.

Community-acquired pneumonia is a major global health challenge that disproportionately affects vulnerable populations, including older people, immunocompromised people, those with chronic conditions, ...

The indolent lymphoma market is witnessing steady growth driven by the increasing prevalence of slow-growing non-Hodgkin ...

Researchers at the University of Missouri School of Medicine have recently found that a certain protein may have a large ...