Since the 1970s, countless experts and the US government have sold the public a simple explanation for drug addiction, now clinically called substance abuse disorder: the myth of the gateway drug.

THE SAN FRANCISCO Department of Public Health is aiming to treat the underlying cause of drug addiction in order to mitigate the city’s overdose deaths, which averaged at least two people dying every ...

How political red tape and a drug company’s thirst for profits limited the reach of a drug that experts believe could have reduced the opioid epidemic’s toll. Credit...Photo illustration by Ben Denzer ...

Experts call for rehabilitation instead of jail time for people with addiction. Drug and alcohol-related jail deaths have skyrocketed in recent years, according to a recent report from the Bureau of ...

"American Pie" actor Jason Biggs is pulling back the curtain on the darkest days of his drug addiction—and the harrowing lengths he went to feed it. Biggs, now 47, revealed a startling glimpse into ...

Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

Ion channels have been created that are selectively activated by cocaine and that act to either stimulate or inhibit the electrical activity of neuronal cells in the brain. These cocaine-activated ion ...