All life on Earth shares a common ancestor that lived roughly four billion years ago. This so-called "last universal common ...

Membrane proteins are vital for cellular signaling, transport, and communication, making them attractive drug targets despite their challenging properties. Advances in mass spectrometry have enabled ...

Ancient duplicated genes are giving scientists their first real clues about what life was like before all life on Earth shared a common ancestor.

BACKGROUND: The disruption of the blood–brain barrier (BBB) is a central pathogenic event in many central nervous system disorders. However, the mechanisms regulating BBB function remain incompletely ...

All life on Earth shares a common ancestor that lived roughly four billion years ago. This so-called "last universal common ancestor" represents the ...

Small-molecule mitochondrial transcription factor A modulators stabilize mtDNA, preventing cytosolic escape and suppressing cGAS-STING interferon signaling, while improving bioenergetics and fibrosis ...

Protein folding helpers such as TRiC and prefoldin (PFD) are crucial for the correct folding of many essential proteins. In a Nature study, researchers from the Max Planck Institute of Biochemistry ...

More than 150 human diseases — including Lou Gehrig’s, Parkinson’s and Alzheimer’s — are linked to mitochondrial failure, and one Nebraska scientist is working to decode why. A five-year, $2 million ...

Scientists kept a patient alive using artificial lung system for 48 hours to clear a deadly infection before a successful ...

Drug discovery requires two separate steps: checking whether a drug can bind to a harmful molecule or its receptor, and ...

City Hall will see the launch of a new department on Tuesday designed to coordinate and strengthen the management of large ...