The eukaryotic structural maintenance of chromosomes (SMC) complexes cohesin, condensin and the SMC5/6 complex organize chromosome structure through their association with DNA and influence a large ...

Cell biologists have found a key clue in the mystery of how chromosomes are inherited correctly every time a cell divides. Using a novel cell probe, they unraveled how a 'matchmaker' molecule stops ...

Sister chromatid exchanges (SCE) and chromosome aberrations were induced in nondividing CHO cells that had been arrested in their cell cycle by deprivation of the essential amino acid arginine. Cells ...

Osaka, Japan - Before cell division when a parent cell divides into two daughter cells, each with an identical set of genetic information, replicated chromosomes become condensed and align along the ...

Scientists succeeded in removing the extra copy of chromosome 21 in cell cultures derived from a person with Down syndrome. Persons with this condition have three copies of this chromosome. The method ...

ChromTR, a cutting-edge framework for chromosome detection in metaphase cell images, represents a significant advancement in the field of cytogenetics. This framework, which integrates semantic ...

Raheel Shafi, Sai Prasad N. Iyer, Lesley G. Ellies, Niall O'Donnell, Kurt W. Marek, Daniel Chui, Gerald W. Hart, Jamey D. Marth Proceedings of the National Academy of Sciences of the United States of ...

For a living cell to divide successfully, each daughter cell must inherit the correct genetic material. In eukaryotes, segregation of duplicated chromosomes is performed by the mitotic spindle, a ...

The well-established existence of sex differences in immune responses, including immune responses driven by T cells, cuts both ways. Females tend to have a stronger immune response to pathogens, yet ...

Frequent fliers, take note. Scientists have figured out how cells quickly pack long chromosomes into compact, organized bundles — a key step before cells divide. The new finding unifies two competing ...

Adolescents and young adults (AYAs) with Philadelphia chromosome–negative acute lymphoblastic leukemia (ALL) represent a unique patient population with a disproportionate survival disadvantage ...