In each female cell, one X chromosome must be inactivated—crumpled up in such a way that the genetic code it contains cannot be read out. RNA plays an important role in this inactivation process.

Because skewed X-inactivation is common in humans, differences can arise not only between the sexes but also between individual women. Abdulai-Saiku et al. investigated how the X chromosome ...

UCSF researchers found that brain cells age more quickly when they rely solely on the X chromosome inherited from a female's ...

The X contains more genes related to brain function than does any other chromosome. “The X chromosome may be a treasure trove ...

A UCSF study reveals that maternal X chromosome expression may accelerate brain aging and cognitive decline. Female mice with ...

But in every cell of their body, just one X chromosome is needed—so the other is randomly inactivated. Some cells use only a maternal X chromosome; others rely only on the paternal X.

Women are born with two X chromosomes and inherit one from each parent. But in every cell of their body, just one X chromosome is needed – so the other is randomly inactivated. Some cells use only a ...

Inactivation of either the maternal or paternal X chromosome causes X mosaicism, and this varies between female individuals, the researchers explained, “… with some showing considerable or ...