LATS1/2-inactivation and consequent nuclear YAP/TAZ hyperactivation in the mammary epithelium drives the development of a pro ...

Researchers at Linköping University in Sweden made an unexpected discovery while investigating genetically unique women.

In cats, the fur pigmentation gene is X-linked, and depending on which copy of the X chromosome each cell chooses to leave active, either an orange or black coat color results. X inactivation only ...

Researchers at Linköping University in Sweden made an unexpected discovery while investigating genetically unique women.

Inactivation also explained why XO female mice were able to survive with a single X chromosome. In her second paper on this subject (1962), Lyon extended her analysis to other species, including ...

In each female cell, one X chromosome must be inactivated—crumpled up in such a way that the genetic code it contains cannot be read out. RNA plays an important role in this inactivation process.

The silencing of the one X chromosome in XX cells is mediated by XIST, a long noncoding RNA that is randomly transcribed from only one X early in development. It coats the DNA and shuts down gene ...

The X contains more genes related to brain function than does any other chromosome. “The X chromosome may be a treasure trove ...

During early female development, one of the two X chromosomes is transcriptionally silenced through X inactivation. This ensures that females produce a similar number of X chromosome gene products to ...

UCSF researchers found that brain cells age more quickly when they rely solely on the X chromosome inherited from a female's ...