To accomplish this, the DNA becomes highly compacted into the classic metaphase chromosomes that can be seen with a light microscope. Once a cell has divided, its chromosomes uncoil again.

Ultraviolet (UV) radiation from the sun is a well-known cause of DNA damage, which can lead to diseases like skin cancer. But ...

Science never ceases to amaze us, and one of the most mind-blowing facts about the human body is the sheer length of our DNA.

Researchers have uncovered a source of "replication stress" during DNA replication, shedding light on a new cancer target.

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop ...

DNA molecules are large and complex. They carry the genetic code that determines the characteristics of a living organism. The diagram shows the relationship between the cell, its nucleus ...

A new study has been published in Nature Communications, presenting the first comprehensive atlas of allele-specific DNA ...

Our DNA is constantly under threat — from cell division errors to external factors like sunlight and smoking. Fortunately, ...

Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...

Two new studies uncover how DNA folding controls sperm cell development. Researchers identified proteins that rearrange ...

Using single-cell RNA sequencing, we mapped thousands of expression quantitative trait loci in yeast, including a variant in GPA1 that influences gene expression, cell-cycle occupancy, and mating ...

This image depicts the chemical structure of cytosine. It shows a hexagonal ring with nitrogen atoms ... These analogs can interfere with DNA replication and induce cell death in rapidly dividing ...