A closeup look at colibactin’s structure reveals chemical motifs that guide its mutation-wreaking “warheads” to specific stretches of DNA.

Colibactin is a powerful toxin produced by Escherichia coli and other bacteria living in the human gut. This highly unstable ...

Chemical insight into biological function is the holy grail of structural biology. Small molecules are central players as building blocks, effectors and probes of macromolecular structure and function ...

Professor Dongsheng Liu of Tsinghua University, Professor Ziyang Hao of Capital Medical University, and Researcher Yuanchen ...

RNA, widely known from the COVID-19 vaccine, is not actually a "therapeutic agent," but a technology that delivers the ...

The microbe Pyrodictium abyssi is an archaeon—a member of what's known as the third domain of life—and an extremophile. It ...

The intriguing findings bolster the theory that asteroids seeded the early Earth with life's chemical components - a process ...

We have long struggled to determine how the first living organisms on Earth came together. Now, surprising evidence hints ...

THIS book is lineal successor in a series of famous books dealing with structural chemistry from a physical point of view, the first of the line being G. N. Lewis's “Valence and the Structure of Atoms ...

Chemists can now precisely control the stereochemical sequence of synthetic polymers using similar techniques to those used ...

For the first time, chemists have fully synthesized verticillin A, a notoriously complex fungal molecule with striking anticancer potential.