The findings, published in Nature Structural & Molecular Biology on February 28, 2025, illuminate how Pol-theta undergoes a major structural rearrangement when it binds to broken DNA strands.

You have full access to this article via your institution. Figure 1: Reduced survival and increased tumor incidence in Pold1 D400A/D400A mice.

Environments are littered with the DNA of the creatures that inhabit them. Analyzing it could provide a real-time view of how our planet is changing. When you purchase through links on our site ...

Stanford Medicine researchers sifted through thousands of single nucleotide mutations in DNA to identify fewer than 400 that are functionally associated with inherited cancer risk. Thousands of ...

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Ancient DNA is telling us more and more about humans and environments long past. Could it also help rescue the future? Eske Willerslev was on a tour of Montreal’s Redpath Museum, a Victorian-era ...

Consequently, numerous analysts eagerly anticipate the future valuation of its native cryptocurrency, POL. This raises the question: Can POL’s price reach $10? This forecast for Polygon’s price ...