北京时间2025年6月4日晚间，复旦大学徐彦辉研究团队在《自然》（Nature）杂志在线发表题为“Structural insights into human Pol III transcription initiation in ...

经济观察网讯 据分子植物科学卓越创新中心消息，近日，中国科学院分子植物科学卓越创新中心巫永睿团队与张余团队，联合上海师范大学王文琴团队，发现了植物质体DNA（ptDNA）复制体中RNA引物切除的核心核酸酶组分plastid-localized and Mn2+-dependent 5′-3′exonuclease ...

尽管 Pol III 进入延伸状态后，与通用转录因子的直接相互作用被打破，但这些因子仍稳定结合在启动子上游区域（图 3）。 长期以来，科学界推测 Pol III 起始因子在一次转录完成后不会立即脱离 DNA，而是保留在启动子附近，便于迅速启动新一轮转录。

Pol III This holoenzyme is the main polymerase in E.coli DNA replication and is one of the family C polymerases. Polymerase III is made up of the clamp-loading complex, the beta sliding clamp ...

This interferes with the processivity of pol III which acts as a checkpoint, stopping replication and allowing time for DNA to be repaired.

The pol II promoter is the region that involves the binding of RNA polymerase II to initiate DNA transcription (Venter and Botha, 2010). On the other hand, polymerase III aids the exclusive ...

RNA polymerase (Pol) III transcribes small untranslated RNAs such as 5S ribosomal RNA, transfer RNAs, and U6 small nuclear RNA. Because of the functions of these RNAs, Pol III transcription is best ...

In the eukaryotic nucleus, RNA Pol III catalyses the DNA-dependent synthesis of short RNAs that are essential for cellular functions, such as tRNAs, the 5S rRNA and the U6 spliceosomal small ...

DNA replication is carried out by a multifunctional machine, the replisome (Beattie and Reyes-Lamothe, 2015). The E. coli replisome has been characterized in vitro and in vivo and is composed of more ...

DNA tests have confirmed that the ancient bones found under a car park in Leicester are those of Richard III – but they also point to a sex scandal in his family tree.