In the Sept. 1 issue of G&D, Drs. Rudra Dubey and Marc Gartenberg reveal a surprising new role for tDNAs and RNA polymerase III-associated proteins in sister chromatid cohesion.

Pol I begins the process of DNA elongation at a point called the “origin of replication” and about 400 base pairs downstream of this point, Pol III takes over replication, which it performs at ...

Finally, DNA ligase III ligates the newly introduced nucleotide with the downstream sequence (5), ... the gap created by the excision of the damaged strand is resynthesized by DNA pol δ/ε, ...

DNA polymerase III is the main family C polymerase involved in E.coli DNA replication. Polymerase III is made up of the clamp-loading complex, the beta sliding clamp processivity factor and the ...

Similarly, lowering 5fC levels by TDG overexpression impaired Pol III binding to tRNA genes and inhibited, rather than activated, their expression. The discovery of 5fC as just the second DNA ...