RNA polymerase (Pol) III has a noncanonical role of viral DNA sensing in the innate immune system. This polymerase transcribes viral genomes to produce RNAs that lead to induction of type I ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 84, No. 12 (Jun. 15, 1987), pp. 4195-4199 (5 pages) Strains of Escherichia coli possessing the pcbA1 mutation, a ...

In the September 1st issue of G&D, Drs. Rudra Dubey and Marc Gartenberg (UMDNJ) reveal a surprising new role for tDNAs and RNA polymerase III-associated proteins in sister chromatid cohesion. Sister ...

The mammalian DNA repair process has evolved over time into a number of complex pathways to cope with all of the alterations that can occur to the structure of DNA. The past 30 years have seen a great ...

Jane Devenish-Meares does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations ...