Cells are constantly subjected to DNA damage from a range of internal and environmental sources. It is estimated that cells can experience as many as 100,000 DNA lesions per day. One of the most ...

When DNA breaks inside the cell, it can spell disaster, especially if the damage occurs in areas of the genome that are difficult to repair. Now, scientists Irene Chiolo and Chiara Merigliano at ...

Additionally, we found that RNA aids in double-strand break repair in both yeast and human cells, suggesting that its role in DNA repair is evolutionarily conserved across species.

Notably, they were able to reintroduce ZNF280A into these cells which partially rescued these DNA repair defects, confirming that the absence of ZNF280A is a key driver of the DNA repair defects in ...

Tumors often show high levels of PDI, where cancer cells appear to exploit its DNA repair abilities to help them survive and resist treatment. "PDI is like a double agent," Dr. Shadfar explains.

Background The frequency of cancer, neurologic degeneration and mortality in xeroderma pigmentosum (XP) patients with defective DNA repair was determined in a four decade natural history study.

Repare Therapeutics Inc. (NASDAQ: RPTX) is one of the best Canadian stocks with huge upside potential. As May began, Repare ...

Aging is the primary risk factor for neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis ...

A major global study tested whether European-derived polygenic risk scores (PGS) for Alzheimer’s disease can predict risk across diverse populations. While PGS performed well in many groups, it ...

For a significant number of people, especially the affluent, the appeal of NAD+ IV drips is immensely noticeable and compelling. Most users claim it has a plethora of benefits, including, but not ...

Dateline often returns to cases that never fully settled. Justice for Meghan is one of those episodes. The crime itself happened in 2008, but the story still feels current.