Jan. 15, 2025 — While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows.

Neurons lack the ability to replicate their DNA, so they're constantly working to repair damage to their genome. A new study finds that these repairs are not random, but instead focus on ...

, have, for the first time, been able to view how this repair machinery prioritizes fixing these thousands of instances of DNA damage. They achieved this feat using their novel sequencing technique, ...

Since the discovery of CRISPR/Cas9, also known as molecular scissors, scientists around the world have been working to improve the revolutionary technique for altering DNA that earned Emmanuelle ...

More information: Ninadini Sharma et al, Changes in DNA repair compartments and cohesin loss promote DNA damage accumulation ...

Please use one of the following formats to cite this article in your essay, paper or report: APA. Sidharthan, Chinta. (2024, March 31). DNA repair process key to memory formation, study finds.

During repair, the DNA reads the uracil as thymine. Although there's no double-stranded break, base editors do create a nick in one strand. An enzyme is attached to the Cas9 and chemically changes ...

When a DSB happens in DNA, it’s like a load-bearing beam in a building breaking. A careful, precise repair is needed to ensure the building’s — or the DNA’s — stability. The pieces must be rejoined ...

Background: ENZA is approved to treat men with mCRPC. TALA is a dual-mechanism PARP inhibitor that inhibits PARP1 and PARP2 catalytic activity and traps PARP on DNA, preventing DNA damage repair and ...

To the point. DNA repair: Plants repair damaged DNA quickly to protect their genome. This repair provides protection against foreign DNA from chloroplasts. Genome stability: Research shows that rapid ...