Our DNA is constantly under threat — from cell division errors to external factors like sunlight and smoking. Fortunately, ...

How do DNA repair mechanisms detect and repair damaged DNA, and what happens when they fail? Defects in DNA repair underlie a number of human genetic diseases that affect a wide variety of body ...

Lung cancer, a leading cause of cancer-related deaths globally, is characterized by significant genomic instability, which is a hallmark of various cancers.

The genetic connections between DNA repair pathways and human cancer predisposition have fueled interest in the proteins that recognize and repair specific sites of DNA damage. The repair enzymes are ...

DNA damage and repair refers to the creation and correction of DNA lesions that threaten genome integrity. Because DNA replication errors or environmental agents that damage DNA can introduce ...

"The surprising result of our research is that DNA repair, which normally protects healthy cells, determines how cancer cells die following radiotherapy," said Prof Cesare. "The DNA inside our ...

Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs) and collapsed replication forks. The fundamental reaction in homologous recombination is the exchange of ...

PARylation is integral to many key cellular functions, including signaling modulation and DNA repair. PARylation is reversible and is undone by PAR erasers such as poly ADP-ribose glycohydrolase (PARG ...

Thus, a 30-year-old woman has egg cells that are just as old. The egg cell’s ability to repair damage in its DNA is crucial to ensure that it remains functional for a long time and does not die. To ...

A study, which was published in the journal Occupational & Environmental Medicine, found that melatonin seems to help actually some people repair DNA damage while sleeping. As you may know ...

A study, which was published in the journal Occupational & Environmental Medicine, found that melatonin seems to help actually some people repair DNA damage while sleeping. As you may know ...