Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...

Researchers at The Institute of Cancer Research, London, have uncovered how the DNA repair enzyme XPF-ERCC1 is recruited to sites of damage and activated inside cells, resolving a long-standing ...

A team of researchers have identified a fundamental mechanism that links the 24-hour circadian cycle to the precise repair of DNA breaks. This study, conducted by researchers from the Andalusian ...

As people age, their immune systems deteriorate. This makes them more susceptible to infections and can mean that vaccines ...

A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most powerful genetic "on switches" in cancer cells, called super-enhancers, drive ...

For decades, grey hair has been treated as a cosmetic nuisance or a simple marker of age. Emerging research now suggests ...

A large genetic study shows that many people carry DNA sequences that slowly expand as they get older. Common genetic variants can dramatically alter how fast this expansion happens, sometimes ...

Sleep is essential for much of the animal kingdom. During the night, neuron and tissue repair mechanisms are activated to aid ...

Swimming at a crawl with cloudy eyes and mottled skin, the Greenland shark looks like it's seen better days. The shark's eyes were thought to be barely functional, as it spends most of its time in ...

Autophagy a self-eating process where the body’s cells recycle their own damaged components to maintain health Our experts ...

Scientists pinpoint age 44 as the surprising tipping point when your body's decline suddenly accelerates—but the gap between ...

The Institute of Cancer Research has welcomed NICE’s recommendation of talazoparib in combination with enzalutamide for adults with metastatic prostate cancer, providing a new treatment option for ...