Franklin W. Stahl, an American molecular biologist whose landmark 1957-58 experiment with colleague Matthew Meselson revealed ...

单细胞转录组分析显示，dna 损伤响应基因（如 cdkn1a、fas、gadd45a）的表达异质性增加，且细胞周期调控基因是异质性的主要驱动因素。 此外，53BP1 的核浓度限制了其焦点形成，细胞间 53BP1 水平的差异直接影响对 DNA 损伤的响应，进一步加剧了异质性。

He and a colleague proved a theory advanced by the Nobel Prize winners James Watson and Francis Crick, who discovered DNA’s ...

Xing Kang et al, Extrachromosomal DNA replication and maintenance couple with DNA damage pathway in tumors, Cell (2025). DOI: 10.1016/j.cell.2025.04.012.

It has genes for ribosomes, tRNAs, and mRNAs. These components are the scaffolding of life: the tools by which cells read ...

DNA replication, the basis for biological inheritance, is a fundamental process occurring in all living organisms to copy their DNA. This process is "semiconservative" in that each strand of the ...

It follows a previous report showing that the Werner syndrome protein WRN and its interacting protein WRNIP1 are indispensable for translesion DNA synthesis (TLS) by Y-family DNA polymerases (Pols).

New imaging tools reveal how within an hour of infection, the virus begins to alter our chromosomes to kick-start its own replication.

Drs Ursula A. Matulonis and Joyce F. Liu discuss targeting DNA damage and repair and replication stress in endometrial cancer.

Revise the structure and replication of DNA for your Higher biology exam with Bitesize Scotland interactive practice quizzes covering feedback and common errors.