在细胞分裂前，DNA 会精准复制出两份相同的 "姐妹染色单体"，它们被环状的黏连蛋白（cohesin）紧紧束缚，直到分裂时被纺锤丝拉向细胞两极—— 这一过程如同一场精密的 "微型拔河"。黏连蛋白虽在近 30 ...

An international research team has determined the first high-resolution structures of the herpes simplex virus origin-binding ...

DNA replication is a fundamental process essential for bacterial growth and survival. Initiation begins at the chromosomal origin (oriC), where the conserved initiator protein DnaA assembles into an ...

如今，梅奥诊所团队发表在 《Nature》 的研究，找到了 DNA “交通拥堵” 的解决者——蛋白质 KCTD10，它像精准的交通指挥官，能及时疏通冲突，守护基因组稳定，更为抗癌治疗开辟新路径。

Scientists have discovered how LINE-1, a “jumping gene” that makes up 17% of the human genome, inserts itself into DNA. Using ...

Researchers at Spain’s CNIO have mapped 20,000 distinct DNA repair “scars,” building the first human REPAIRome. This atlas reveals how each human gene shapes DNA repair after double-strand breaks.

Mayo Clinic researchers have identified a protein that acts like a traffic controller for DNA, preventing damage during cell division — a discovery that could lead to new cancer therapies, according ...

An international research team has successfully identified the initial high-resolution structures of the herpes simplex virus ...

A study reveals the secrets behind the rodent’s remarkable ability to live 10 times longer than expected, without cancer or ...

The rate of HIV infection continues to climb globally. Around 40 million people live with HIV-1, the most common HIV strain.

Companies that make DNA for science labs screen out any requests for dangerous bits of genetic material. But a new study ...