The SUMO ligase activity of ... a converging fork will complete replication. However, if a single fork stops within the rDNA or telomere, it will result in a region of DNA that cannot be replicated.

Univ Brest, Ifremer, Biologie et Ecologie des Ecosystèmes Marins Profonds (BEEP), Plouzané, France In my opinion, these discoveries challenge the “classical” models of DNA replication. Archaea are not ...

Each replication fork synthesises a leading strand in the same direction as the fork progression and a lagging strand synthesised as 100-200bp discontinuous Okazaki fragments in the opposite direction ...

The breaks are caused by a variety of things, including normal cellular processes like DNA replication ... The enzyme DNA ligase 4 is also needed to make vital proteins on the surface of immune ...

Xiang et al. investigated the role of ubiquitin E3 ligase ITCH in SARS-CoV-2 replication. First, they described the role of ITCH on the structural proteins. Here, the ubiquitination of E and M (but ...

This valuable study presents findings on DNA methylation as an efficient epigenetic transcriptional regulating strategy in bacteria. The authors utilized single-molecule real-time sequencing to ...

The number of home DNA test kits offering nutrition and diet advice matched to your genes is growing. They’re based on the idea that each of us responds to foods differently, in part due to our ...

Stanford Medicine researchers sifted through thousands of single nucleotide mutations in DNA to identify fewer than 400 that are functionally associated with inherited cancer risk. Thousands of ...

When you purchase through links on our site, we may earn an affiliate commission. Home DNA tests are an accessible way to gain an extensive understanding of your heritage, family history and diaspora.

Ancient DNA is telling us more and more about humans and environments long past. Could it also help rescue the future? Eske Willerslev was on a tour of Montreal’s Redpath Museum, a Victorian-era ...