Significant advancements in gene silencing and gene editing offer new hope for treating rare disorders. Techniques like RNA ...

Despite setbacks and funding cuts — and a quieting of the hype blaring its arrival — multiple CRISPR-based trials are ...

Since 2019, MIT researchers have published a new concept called prime editing, which is more precise than regular CRISPR-Cas9 gene editing. As a result, it has fewer off-target effects and less chance ...

The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kongens Lyngby, Denmark ...

本研究通过概念验证表明，序列上下文驱动的断裂概率能有效提升超短片段组装质量。虽然当前实现为简化模型，但为核心算法集成奠定基础：未来将概率评估嵌入de ...

CRISPR-based tools can’t easily access the DNA in these organelles, but researchers are finding other ways in.

Abstract: In DNA sequencing, we often need to infer an unknown sequence from a collection of its corrupted copies. Each copy cannot faithfully tell the truth due to DNA fragmentation, point mutations, ...