Using an inexpensive electrode coated with DNA, MIT researchers have designed disposable diagnostics that could be adapted to ...

Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a ...

In this communication, we show that peptide nucleic acids (PNAs) with lengths of 15−20 nucleotides, when preorganized into a right-handed helix, can invade mixed-sequence double-helical B-form DNA ...

Universal Primer technology is used to crack wildlife crime cases, from ivory trafficking in Odisha to illegal bushmeat ...

The collapse of DNA replication forks leads to the formation of single-ended DNA double-strand breaks. One would have assumed that these breaks would be repaired as soon as possible.

A computational model simulating how DNA sequence repeats influence gene inversions and strand bias in bacterial genomes. Abstract This project investigates how different DNA repeat configurations ...

The promise of genome editing to help understand human diseases and create new therapies is vast, but technological ...

Experiments with tools designed to detect DNA damage reveal unique and conserved features of telomeres in cancer cells.

It follows a previous report showing that the Werner syndrome protein WRN and its interacting protein WRNIP1 are indispensable for translesion DNA synthesis (TLS) by Y-family DNA polymerases (Pols).

Manipulating DNA repair proteins to improve gene editing outcomes. by Michelle Franklin, ... Although there's no double-stranded break, base editors do create a nick in one strand.