为探究 DNA-PKcs 非经典功能，研究人员聚焦其在 RNA 代谢中的作用，发现其与多种疾病相关，为肿瘤治疗提供新方向。 在生命的微观世界里，基因的稳定表达就像精密仪器的正常运转，任何故障都可能引发严重后果。DNA 损伤在 ...

DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease ...

RNA，作为生命活动的中心分子之一，其功能远不止于转录 DNA 信息。近年来，RNA 的结构多样性及其在生物学过程中的关键作用越来越受到关注，研究 ...

在生命科学领域,DNA(脱氧核糖核酸)与RNA(核糖核酸)常被统称为“核酸”,但这一笼统归类可能掩盖了二者本质差异,甚至对医学诊断产生误导。近日,多 ...

为探究 dna 甲基转移酶 1（dnmt1）相关突变导致迟发性神经退行性疾病的机制，研究人员开展了关于 dnmt1 与 rna 甲基化及线粒体功能关系的研究。 结果发现 DNMT1 可调节 RNA m5C 甲基化影响线粒体功能，为相关疾病致病机制研究提供新视角。

研究发现RNA通过一个名为TET2的基因，在DNA如何包装和储存在细胞中起着重要作用。 在每个细胞内，在每个细胞核中，你的持续生存取决于一场极其 ...

No longer a mere assistant who carries out the commands of DNA, RNA takes the lead in emerging therapeutics.

In Biology 101, we learn that RNA is a single, ribbon-like strand of base pairs that is copied from our DNA and then read like a recipe to build a protein. But there's more to the story. Some RNA ...

Linked to neurological disorders, repeat RNAs aggregate inside droplets but can be disassembled with an engineered piece of ...

A strategy that analyzes the structural properties of RNA could help identify regions that are promising targets for antiviral drugs.

Accurate measurement of DNA or RNA concentration and purity is fundamental for many downstream processes, including transfection, electroporation, cloning, PCR and NGS. 1, 2 Without proper ...