LIG4 syndrome is an exceptionally rare disorder caused by a genetic mutation that prevents the body from repairing damaged ...

Many people follow the golden rules of avoiding direct sunlight between the hours of noon and 3 p.m., staying in […] ...

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means ...

If these DNA breaks aren't repaired, they can prompt cells to self-destruct, or failing that, become cancerous.As LIG4 syndrome impairs this response, people with the condition are particularly ...

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means ...

Most dividing cells in the body have well-defined checkpoint mechanisms to sense and correct DNA damage during DNA replication. Neurons, however, do not divide. For this reason, they are at ...

Ever since scientists discovered DNA’s crucial role in life, they’ve known our cells have built-in repair systems to fix damaged genetic material. But recent research has revealed something unexpected ...

Sunburn has traditionally been attributed to UV-induced DNA damage, but it turns out that this is not the full truth. That’s according to a study from the University of Copenhagen and Nanyang ...

"Sunburn damages the DNA, leading to cell death and inflammation. So the textbooks say. But in this study we were surprised to learn that this is a result of damage to the RNA, not the DNA that ...

Perturbations to either property can have pathological consequences. Predominant sources for replication stress are DNA lesions, such as those induced by oxidative damage. How mtDNA lesions affect the ...

DNA damage can persist unrepaired for years, particularly in blood stem cells, increasing the risk of mutations and cancer. This discovery challenges traditional views on mutation processes and ...