We recommend using your OS's package manager directly instead for improved security but the install script is by no means insecure. In addition to being a runnable CLI tool, D2 can also be used to ...

The crystal structure of pseudouridine synthase I from Escherichia coli, which, for example, modifies positions 38, 39 and/or 40 in tRNA, reveals a dimeric protein that contains two positively ...

Institute of Agrobiological Sciences, National Agriculture and Food Research Organization (NARO), 1-2 Owashi, Tsukuba, Ibaraki 305-8634, Japan ...

eIF2A has minimum effect on cell proliferation and global translation. (A) Validation that eIF2A knockout cells have no eIF2A protein by immunoblotting. (B) Two ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. This paper presents a grid-based approach to model molecular association processes as ...

This manuscript provides important structural insights into the recognition and degradation of the host tRNA methyltransferase TRMT1 by SARS-CoV-2 protease nsp5 (Mpro). The data provide compelling ...

Protein synthesis is a central process in microorganisms and is heavily targeted by antimicrobials. Studies of transfer RNAs (tRNAs), aminoacyl-tRNA synthetases (aaRSs), and ribosomes have led to ...

From accounting to business analytics, finance to supply chain management, Price students are ready to lead in a changing world. Whether you're a budding entrepreneur with a billion-dollar idea or a ...

To determine the mechanism underlying the flow of genetic information, it is important to understand the relationship between a tRNA and its binding enzyme, a member of the aminoacyl-tRNA synthetase ...