Rett syndrome is a devastating rare genetic childhood disorder primarily affecting girls. Merely 1 out of 10,000 girls are ...

FDA's plan to phase out animal testing may hurt Charles River's revenues. The DCF model suggests that CRL presents an ...

Proteins have specific biological functions in cells through conformational changes and interactions. Therefore, precise, in ...

AbbVie gains control of an in vivo CAR-T therapy that could overcome limitations with currently approved autologous ...

The acquisition will expand AbbVie's exploration of in vivo CAR-T therapy, an ambitious approach that could sidestep some of ...

This process is known as metabolic glycan labeling and has shown promise in targeted drug delivery systems. Wang's lab had previously demonstrated successful metabolic labeling in cancer and ...

Prostate cancer is one of the most common malignancies in men globally. Hormonal therapies targeting the androgen–androgen ...

The entire process can take weeks, though many companies are working on ways to make it faster and more efficient. In vivo engineering of a patient’s immune cells would avoid this expensive ...

AI-enabled drug discovery approach identified potentially game-changing treatment which has been advanced from the lab bench to an FDA Orphan Drug ...

An international research team, including scientists from the Institut de Neurociències at the Universitat Autònoma de ...

Instead of extracting T-cells and engineering them in a lab, researchers have delivered mRNA directly into circulating immune ...

This process requires the synthesis of extracellular matrix (ECM) in the bone growth plates. Bone growth occurs through the proliferation of specialized cells of the cartilage tissue, known as ...